CYTOCON DB Open change log
CYTOCON DB 1.7.5.57 | 05.11.2024.
The DB was extended with new data: 5 diseases, 2 tissues, 4 cell types and 836 concentrations were introduced. For this purpose 34 articles were reviewed.
CYTOCON DB 1.7.5.56 | 10.10.2024.
The algorithm of outliers search was included into the DB: concentrations in unified units out of +/-1,5*IQR interval are analyzed, approved, marked in the results table and excluded from the calculation of weighted mean and SD values.
Patients subgroups are marked in the results table and their concentration values are not included in the weighted statistics calculation to avoid overestimation of the values assigned to the same patients from different overlaped groups.
Molecular weights are introduced to the DB from PubChem and UniProt according to molecules IDs to recalculate original units (i.e. pg/mL) to unified units (pM).
The DB was extended with new data: 24 diseases, 1 tissue, 6 molecules, 10 cell types and 1615 concentrations were introduced. For this purpose 43 articles were reviewed.
CYTOCON DB 1.6.5.55 | 10.09.2024.
The DB was extended with new data: 10 diseases, 3 tissues, 3 molecules, 2 cell types and 1555 concentrations were introduced. For this purpose 46 articles were reviewed.
CYTOCON DB 1.6.5.54 | 10.08.2024.
The DB was extended with new data: 10 diseases, 7 molecules, 3 cell types and 1860 concentrations were introduced. For this purpose 34 articles were reviewed.
CYTOCON DB 1.6.5.53 | 10.07.2024.
“Calculate weighted statistics” option was added to the Query page. It allows to obtain weighted mean and SD value for a set of cell/molecule concentrations uploaded to the results table. The DB was extended with new data: 8 diseases, 1 tissue, 11 molecules, 2 cell types and 1383 concentrations were introduced. For this purpose 37 articles were reviewed.
CYTOCON DB 1.5.5.52 | 10.06.2024.
The DB was extended with new data: 8 diseases, 1 tissue, 5 molecules, 4 cell types and 1451 concentrations were introduced. For this purpose 44 articles were reviewed.
CYTOCON DB 1.5.5.51 | 10.05.2024.
The DB was extended with new data: 7 diseases, 15 molecules and 1486 concentrations were introduced. For this purpose 52 articles were reviewed.
CYTOCON DB 1.5.5.50 | 10.04.2024.
The DB was extended with new data: 3 diseases, 9 molecules and 1789 concentrations were introduced. For this purpose 63 articles were reviewed.
CYTOCON DB 1.5.5.49 | 11.03.2024.
The DB was extended with new data: 8 diseases, 2 tissues, 9 molecules and 1639 concentrations were introduced. For this purpose 63 articles were reviewed.
CYTOCON DB 1.5.5.48 | 10.02.2024.
The DB was extended with new data: 3 diseases, 2 tissue, 35 molecules and 1544 concentrations were introduced. For this purpose 58 articles were reviewed.
CYTOCON DB 1.5.5.47 | 10.01.2024.
The DB was extended with new data: 6 diseases, 39 molecules and 1565 concentrations were introduced. For this purpose 45 articles were reviewed.
CYTOCON DB 1.5.5.46 | 10.12.2023.
The DB was extended with new data: 3 diseases, 3 molecules, 4 cells and 1554 concentrations were introduced. For this purpose 35 articles were reviewed.
CYTOCON DB 1.5.5.45 | 10.11.2023.
The DB was extended with new data: 3 diseases, 1 tissue, 7 molecules, 5 cells and 2004 concentrations were introduced. For this purpose 33 articles were reviewed.
CYTOCON DB 1.5.5.44 | 10.10.2023.
The DB was extended with new data: 4 diseases, 2 tissues, 3 molecules, 1 cell and 1522 concentrations were introduced. For this purpose 24 articles were reviewed.
CYTOCON DB 1.5.5.43 | 10.09.2023.
The DB was extended with new data: 1 disease, 6 molecules, 2 cells and 1754 concentrations were introduced. For this purpose 48 articles were reviewed.
CYTOCON DB 1.5.5.42 | 04.08.2023.
The DB was extended with new data: 2 diseases, 3 molecules, 3 cells and 1108 concentrations were introduced. For this purpose 31 articles were reviewed.
CYTOCON DB 1.5.5.41 | 10.07.2023.
The DB was extended with new data: 3 tissues, 5 molecules, 1 cell and 1631 concentrations were introduced. For this purpose 19 articles were reviewed.
CYTOCON DB 1.5.5.40 | 10.06.2023.
The DB was extended with new data: 12 diseases, 16 molecules, 1 cell and 1534 concentrations were introduced. For this purpose 55 articles were reviewed.
CYTOCON DB 1.5.5.39 | 10.05.2023.
PMID field was added to Query page which allows to download the data from certain article. Special unit coefficients and averaged concentration of the ‘parent’ cell as well as “Additional info” section with DB content were added to Supplementary materials. The DB was extended with new data: 10 diseases, 1 tissue, 3 molecules and 1592 concentrations were introduced. For this purpose 36 articles were reviewed.
CYTOCON DB 1.5.4.38 | 06.04.2023.
"Clear form" button was added to Query manager. It allows to clear all fields on the Query page to make a new query. Annotator/Reviewer comment fields were updated. Change log editor was added. The DB was extended with new data: 7 diseases, 2 tissue, 8 cells, 1 molecule and 1741 concentrations were introduced. For this purpose 41 articles were reviewed.
CYTOCON DB 1.5.3.37 | 10.03.2023.
The DB was extended with new data: 4 diseases, 1 tissue, 24 cells and 1290 concentrations were introduced. For this purpose 29 articles were reviewed.
CYTOCON DB 1.5.3.36 | 10.02.2023.
Supplementary materials section was extended with the tissue parameters list used for unit conversion. The DB was extended with new data: 7 diseases, 2 tissues, 4 molecules, 15 cells and 1584 concentrations were introduced. For this purpose 46 articles were reviewed.
CYTOCON DB 1.5.3.35 | 10.01.2023.
The DB was extended with new data: 8 diseases, 6 molecules and 1450 concentrations were introduced. For this purpose 32 articles were reviewed.
CYTOCON DB 1.5.3.34 | 11.12.2022.
The DB was extended with new data: 2 diseases, 1 tissue, 4 molecules, 3 cells and 1693 concentrations were introduced. For this purpose 43 articles were reviewed.
CYTOCON DB 1.5.0.33 | 10.11.2022.
Table result was extended with new columns - Experimental method, Patient group description, Species value description. The DB was extended with new data: 3 diseases, 2 tissue, 1 molecules, 3 cells and 1681 concentrations were introduced. For this purpose 38 articles were reviewed.
CYTOCON DB 1.4.30.32 | 10.10.2022.
Query page was updated. "Query to apply" is the list of pre-saved queries that became available. Now several species instead of one can be chosen from the list. Tissue types and diseases lists are now automatically truncated after species selection according to data availability in the DB. "Query manager" section was implemented. It allows to save new queries and delete unused queries. Two new buttons were added above the table results. They allow to make hidden or visible patient group attributes and disease attributes in the table results. Average type, Dispersion type and Experimental method lists were hidden as unused on the query page. The new column "Species value in ISF" was added to the table results. It contains cell concentrations recalculated to interstitial fluid volume, whereas "Species value" column shows cell concentrations in total tissue volume. "Review statistics" was updated and "Usage statistics" was implemented in frames of the Statistics page. "Failed checks" tool was implemented to reveal outliers for additional control of the annotation process on the Manage page. The PR page was added to perform Query statistics analysis. "Home" button was added to the upper menu to show general DB information including the content of CYTOCON DB and the lists of diseases, tissues, cells and molecules. The manual on the home page was updated with the instructions of search possibilities of the new Query page.
The DB was extended with new data: 6 diseases, 2 tissue, 3 molecules, 4 cells and 2310 concentrations were introduced. For this purpose 43 articles were reviewed.
CYTOCON DB 1.3.9.31 | 10.09.2022.
The DB was extended with new data: 6 diseases, 5 tissue, 11 molecules and 2089 concentrations were introduced. For this purpose 64 articles were reviewed.
CYTOCON DB 1.3.9.30 | 08.08.2022.
The DB was extended with new data: 5 diseases, 1 tissue, 15 molecules, 7 cells and 1506 concentrations were introduced. For this purpose 53 articles were reviewed.
CYTOCON DB 1.3.9.29 | 10.07.2022.
The DB was extended with new data: 18 diseases, 1 tissue, 9 molecules, 1 cell and 2320 concentrations were introduced. For this purpose 49 articles were reviewed.
CYTOCON DB 1.3.9.28 | 11.06.2022.
The DB was extended with new data: 7 diseases, 7 tissues, 4 molecules, 2 cells and 2430 concentrations were introduced. For this purpose 46 articles were reviewed.
CYTOCON DB 1.3.9.27 | 12.05.2022.
The DB was extended with new data: 9 diseases, 4 tissues, 4 molecules and 1963 concentrations were introduced. For this purpose 43 articles were reviewed.
CYTOCON DB 1.3.9.26 | 11.04.2022.
The DB was extended with new data: 7 diseases, 3 tissues, 2 molecules, 1 cell and 1721 concentration were introduced. For this purpose 51 article were reviewed.
CYTOCON DB 1.3.9.25 | 11.03.2022.
The DB was extended with new data: 9 diseases, 11 molecules, 3 cells and 2325 concentrations were introduced. For this purpose 39 articles were reviewed.
CYTOCON DB 1.3.9.24 | 09.02.2022.
Navigation in annotation and reviewing processes was improved. The DB was extended with new data: 4 diseases, 4 tissues, 2 molecules, 2 cells and 1527 concentrations were introduced. For this purpose 43 articles were reviewed.
CYTOCON DB 1.3.8.23 | 09.01.2022.
The DB was extended with new data: 10 diseases, 2 tissues, 11 molecules and 1636 concentrations were introduced. For this purpose 49 articles were reviewed.
CYTOCON DB 1.3.8.22 | 13.12.2021.
The DB was extended with new data: 3 diseases, 3 molecules and 1311 concentrations were introduced. For this purpose 31 articles were reviewed.
CYTOCON DB 1.3.8.21 | 11.11.2021.
The DB was extended with new data: 11 diseases, 9 tissues, 7 molecules and 1493 concentrations were introduced. For this purpose 45 articles were reviewed.
CYTOCON DB 1.3.8.20 | 11.10.2021.
Two new unit types with log2 were added for recalculation of original units to pM and kcells/L (i.e. log2 pg/mL). The DB was extended with new data: 11 diseases, 13 tissues, 2 molecules, 2 cells and 1337 concentrations were introduced. For this purpose 34 articles were reviewed.
CYTOCON DB 1.3.8.19 | 10.09.2021.
Annotation statistics table was extended with two columns - patient group species values taken or calculated and species values digitized. Date range filtering was corrected on statistics page. The DB was extended with new data: 5 diseases, 15 tissues, 19 molecules, 1 cell and 1804 concentrations were introduced. For this purpose 25 articles were reviewed.
CYTOCON DB 1.3.7.18 | 08.08.2021.
The DB was extended with new data: 17 diseases, 10 tissues, 5 molecules, 3 cells and 1490 concentrations were introduced. For this purpose 18 articles were reviewed.
CYTOCON DB 1.3.7.17 | 10.07.2021.
The DB was extended with new data: 13 diseases, 10 tissues, 5 molecules, 14 cells and 1803 concentrations were introduced. For this purpose 33 articles were reviewed.
CYTOCON DB 1.3.7.16 | 10.06.2021.
Review form for patient group special units was corrected. The DB was extended with new data: 14 diseases, 15 tissues, 7 molecules, 2 cells and 1866 concentrations were introduced. For this purpose 36 articles were reviewed.
CYTOCON DB 1.3.6.15 | 10.05.2021.
The DB was extended with new data: 10 diseases, 2 tissues, 4 molecules, 3 cells and 1037 concentrations were introduced. For this purpose 27 articles were reviewed.
CYTOCON DB 1.3.6.14 | 10.04.2021.
The DB was extended with new data: 13 diseases, 3 tissues, 7 molecules, 3 cells and 1573 concentrations were introduced. For this purpose 34 articles were reviewed.
CYTOCON DB 1.3.6.13 | 10.03.2021.
The DB was extended with new data: 10 diseases, 14 tissues, 3 molecules, 2 cells and 1162 concentrations were introduced. For this purpose 27 articles were reviewed.
CYTOCON DB 1.3.6.12 | 10.02.2021.
The DB was extended with new data: 3 diseases, 7 tissues, 1 molecule, 1 cell and 904 concentrations were introduced. For this purpose 19 articles were reviewed.
CYTOCON DB 1.3.6.11 | 10.01.2021.
The DB was extended with new data: 7 diseases, 3 tissues, 15 molecules, 7 cells and 2053 concentrations were introduced. For this purpose 54 articles were reviewed.
CYTOCON DB 1.3.6.10 | 10.12.2020.
The DB was extended with new data: 5 diseases, 2 molecules, 4 cells and 1225 concentrations were introduced. For this purpose 31 articles were reviewed.
CYTOCON DB 1.3.6.9 | 10.11.2020.
The DB was extended with new data: 5 diseases, 4 tissues, 13 molecules, 1 cell and 1221 concentrations were introduced. For this purpose 29 articles were reviewed.
CYTOCON DB 1.3.6.8 | 10.10.2020.
- Concept of "Special units" was proposed and corresponding annotation and review forms were implemented in backend of the database. This tool allows us to include into the DB such kind of units for cell subtypes as % of cells_markers_tissue_disease (percent of "parent" cell characterized by particular set of markers) and to recalculate them to unified units whether cells concentration was measured in the annotated article or not. In the first case the concentration of cell subtypes is calculated on the basis of the concentration of "parent" cell available in the article. In the second case the average concentration of the "parent" cell in the particular tissue and disease is taken from the DB.
- The order of the columns with patient group attributes was changed in the Table results to be more convenient to interpret the data.
- The DB was extended with new data: 7 diseases, 1 tissue, 26 molecules and 1866 concentrations were introduced. For these purposes 28 articles were reviewed.
CYTOCON DB 1.2.6.7 | 10.09.2020.
- The DB was extended with new data: 20 disease, 3 tissues, 24 molecules, 8 cells and 1731 concentrations were introduced. For this purpose 39 articles were reviewed.
CYTOCON DB 1.2.6.6 | 10.08.2020.
- The DB was extended with new data: 9 disease, 13 tissues, 20 molecules, 7 cells and 2525 concentrations were introduced. For this purpose 39 articles were reviewed.
CYTOCON DB 1.2.6.5 | 10.07.2020.
- A change in columns order was done in Table results: now "Patient number" column follows "Source type" column.
- The DB was extended with new data: 1 disease, 3 tissues, 14 molecules and 687 concentrations were introduced. For this purpose 19 articles were reviewed.
CYTOCON DB 1.1.6.4 | 10.06.2020.
- Cell markers case-insensitive search by first letters in Query section was added.
- Reset password form was corrected.
- The DB was significantly extended with new data: 54 diseases, 24 tissues, 42 molecules, 24 cells and 3701 concentrations were introduced. For this purpose 89 articles were reviewed.
CYTOCON DB 1.1.2.3 | 10.05.2020.
- Section Supplementary material was added containing three parts - Unit conversion, Molecular weights and Tissue parameters used for unit conversion.
- Query, Table results, column Unified units is now filled with kcell/L for cells and pM for molecules.
- The bug of the previous version has been fixed: now search for data with selection of two or more diseases is available.
Version A.B.C.D where:
- A - major version;
- B - minor version;
- C - patch version.
- D - data version;
