Cytocon DB

About CYTOCON


CYTOCON (Cell and cYTOkine CONcentrations) is an initiative project undertaken by InSysBio team and aimed at the development of a database that allows collecting, processing and visualizing publicly available data on immune cells and cytokine baseline concentrations in humans.

CYTOCON DB is a database of human baseline concentrations of cytokines and cells measured in different tissues of healthy subjects and patients suffering from various pathologies.

CYTOCON team makes an effort in two directions: the collection and processing of appropriate data on human immune cell and cytokine concentrations available in public domain (content of CYTOCON DB) and the development of tools/methods for processing, extraction and visualization of the data (CYTOCON DB).


Key features of CYTOCON DB:

  • Search for cell/cytokine concentration for selected disease, tissue (or a group of diseases and tissues), patient group.
  • Search query for cell concentration may include a list of cell markers: i.e. for Th2-cell - CD4+, IL4+
  • Search query may include following patient group attributes:
    • demographic characteristics (age, race, gender, etc);
    • number of patients in the study.
  • Search query may take into account disease-specific clinically measured characteristics, for example:
    • Asthma: FEV1;
    • SLE: SLEADAI range, interferon signature;
    • Atopic Dermatitis: SCORAD range, severity, range of IgE concentration;
    • etc.
  • Unification of measurement units: conversion of source original units to “pM” for cytokine and “kcell/L” for cell concentration.
  • Table representation of search results: average value and dispersion of concentration of cell/cytokine in original and unified units, tissue type, data source, patient group and disease attributes are specified.
  • Graphic representation of search results: average value, dispersion, source.
  • Export of search results in csv format

Content of CYTOCON DB:

    • Acinic cell adenocarcinoma
    • Acute allergic reactions
    • Acute coronary syndrome
    • Acute coronary syndrome, nonocclusive type (unstable angina)
    • Acute coronary syndrome, occlusive type (transmural myocardial infarction)
    • Acute hepatitis B
    • Acute lymphoid leukaemia
    • Acute myeloid leukaemia
    • Acute pancreatitis
    • Acute pyelonephritis
    • Adenocarcinoma of bronchus or lung
    • Adenocarcinoma of cervix
    • Adenocarcinoma of oesophagus
    • Adenocarcinoma of stomach
    • Adenoid cystic carcinoma
    • Adenosquamous carcinoma of bronchus or lung
    • Adult T-cell leukaemia/lymphoma (ATLL)
    • adult-onset Still’s disease (AOSD)
    • AIDS
    • Alcohol-induced dementia
    • Allergic asthma
    • Allergic contact dermatitis
    • Allergic rhinitis
    • Alveolar rhabdomyosarcoma
    • Alveolar soft part sarcoma
    • Alzheimer disease
    • Angiosarcoma
    • Ankylosing spondylitis
    • Asthma
    • Asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS)
    • Atopic allergy
    • Atopic asthma
    • Atopic dermatitis
    • Atopy, nonasthma
    • Atypical hyperplasia
    • Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy
    • Bacterial pneumonia
    • Basal cell carcinoma
    • B-cell non-Hodgkin lymphoma (B-NHL)
    • Behçet's disease
    • Benign lung lesions
    • Benign soft-tissue neoplasm
    • Brain trauma
    • Breast cancer
    • Breast carcinoma
    • Bronchial asthma
    • Bronchiectasis
    • Bronchoalveolar carcinoma
    • Bullous pemphigoid
    • Carcinoma
    • CD40L deficiency
    • Celiac disease
    • Central nervous system infection
    • Cerebrovascular disease no-dementia
    • Cervical cancer
    • Cervical intraepithelial neoplasia
    • Chondrosarcoma
    • Chordoma
    • Chronic atrophic gastritis
    • Chronic Bronchial Asthma
    • Chronic bronchitis (COPD)
    • Chronic cough
    • Chronic hepatitis B
    • Chronic Hepatitis C
    • Chronic idiopathic urticaria, hives
    • Chronic kidney disease
    • Chronic liver failure (CLF)
    • Chronic myeloid leukaemia
    • Chronic obstructive pulmonary disease (COPD)
    • Chronic Spontaneous Urticaria
    • Chronic superficial gastritis
    • Clear cell sarcoma
    • Colitis
    • Colitis associated cancer (CAC)
    • Colon adenocarcinoma
    • Colon carcinoma
    • Colonic cancer
    • Colorectal cancer (CRC)
    • Common variable immunodeficiency (CVID)
    • Contact dermatitis
    • COVID-19
    • Crohn's disease
    • Cutaneous Lupus Erythematosus
    • Cutaneous T-cell lymphoma
    • Cyclic neutropenia
    • Cystic fibrosis
    • Dedifferentiated liposarcoma
    • Deep vein thrombosis
    • Dementia with Lewy bodies (DLB)
    • Dengue
    • Depression (6A70.Z Single episode depressive disorder)
    • Dermatomyositis
    • Dermatophytosis
    • Desmoplastic small round cell tumour
    • DFSP dermatofibrosarcoma protuberans
    • Discoid Lupus Erythematosus
    • Dysbacteriosis
    • Dysmyelopoiesis
    • Early arthritis
    • Embryonal rhabdomyosarcoma
    • End stage renal disease
    • Endometrial carcinoma
    • Endometriosis
    • Enthesitis-related arthritis
    • Eosinophilia
    • Eosinophilic asthma
    • Eosinophilic bronchitis
    • Epithelioid sarcoma
    • Epstein-Barr virus (EBV) infection
    • Erythema multiforme
    • Esophageal cancer
    • Esophageal carcinoma
    • Ewing sarcoma
    • Familial lecithin:cholesterol acyltransferase (LCAT) deficiency
    • Familial lipoprotein lipase (LPL) deficiency
    • Fanconi anaemia
    • Fibrotic hypersensitivity pneumonitis
    • Focal segmental glomerulosclerosis
    • Follicular lymphoma
    • Frontotemporal lobe dementia (FTLD)
    • Gastric cancer
    • Gastric ulcer
    • GIST gastrointestinal stromal tumour
    • Gout
    • HBV carriers
    • HBV-related cirrhosis
    • HBV-related HCC (hepatocellular carcinoma)
    • Head and neck cancer
    • Head and Neck Squamous Cell Carcinoma
    • Healthy control
    • Hepatitis B
    • Hepatitis non-infectious
    • Hepatocellular carcinoma (HCC)
    • Human imunodeficiency virus (HIV-1) infection
    • Idiopathic aplastic anemia
    • Idiopathic inflammatory myopathies
    • Idiopathic interstitial pneumonia
    • Idiopathic pulmonary fibrosis
    • IgA glomerulonephriris
    • Immunoglobulin A nephropathy (IgAN)
    • Infections
    • Inflammatory Bowel Diseases
    • Inflammatory breast cancer (IBC)
    • Influenza
    • Interstitial pneumonia with autoimmune features
    • Irritable Bowel Syndrome
    • Juvenile idiopathic arthritis
    • Large cell carcinoma of bronchus or lung
    • Laryngeal Squamous Cell Carcinoma
    • Leiomyosarcoma
    • Liver cirrhosis
    • Low-grade fibromyxoid sarcoma
    • Lung cancer
    • Lupus nephritis
    • Lymphadenopathic mastocytosis with eosinophilia
    • Malignant salivary gland tumors
    • Melanoma
    • Membranous nephropathy
    • Microcrystal arthritis
    • Mild cognitive impairment (MCI)
    • Mild cognitive impairment with Alzheimer’s disease (MCI-AD)
    • Mild cognitive impairment with Lewy body dementia (MCI-LB)
    • Minimal change disease (MCD, minimal change glomerulopathy)
    • Mixed granulocytic asthma
    • MPNST malignant peripheral nerve sheath tumor
    • Mucoepidermoid carcinoma
    • Multiple myeloma
    • Myasthenia gravis
    • Myelodysplastic syndrome
    • Myxofibrosarcoma
    • Myxoid/round cell liposarcoma (MRCL)
    • Neutrophilic asthma
    • Nocturnal Asthma
    • Non-atopic asthma
    • Non-eosinophilic asthma
    • Non-fibrotic lung diseases
    • Non-Hodgkin Lymphoma
    • Non-Hodgkin's lymphoma and Hodgkin's lymhoma patients
    • Non-idiopathic pulmonary fibrosis
    • Non-psoriatic arthritis spondyloarthritis (non-PsA SpA)
    • Non-Small Cell Lung Cancer (NSCLC)
    • Non-squamous bronchial carcinoma
    • Non-translocation sarcoma
    • Novel coronavirus pneumonia
    • Nummular Eczema
    • Obesity
    • Oral lichen planus
    • Oral submucous fibrosis
    • Osteoarthritis
    • Osteoarthritis inflammatory
    • Osteosarcoma
    • Ovarian cancer
    • Pancreatic cancer
    • Parotid gland acinic cell carcinoma
    • Parotid gland myoepithelioma
    • Parotid gland pleomorphic adenoma
    • Parotid gland Warthin’s tumor
    • Paucigranulocytic asthma
    • Pemphigus vulgaris
    • Pleomorphic adenoma
    • Pneumonia
    • Polycythaemia vera
    • Primary bronchial carcinoma
    • Progressive supranuclear palsy (PSP)
    • Prostate cancer
    • Psoriasis
    • Psoriatic arthritis
    • Pulmonary embolism
    • Pulmonary emphysema
    • Reactive arthritis
    • Recurrent depressive disorders
    • Refractory Bone and Soft Tissue Sarcoma
    • Renal carcinoma
    • Renal cell carcinoma
    • Renal dysfunction
    • Respiratory syncytial virus (RSV) pneumonia
    • Rheumatoid arthritis
    • Sarcoidosis
    • Sarcoma
    • Schizophrenia
    • Sclerodermia
    • Sclerosing lymphocytic lobulitis of the breast
    • Seborrheic dermatitis
    • Sepsis
    • Septic shock
    • Sjogrens syndrome
    • Skin cancer
    • Small cell carcinoma of bronchus or lung
    • Small cell lung cancer (SCLC)
    • Soft tissue sarcoma
    • Solid malignant tumors
    • Solitary fibrous tumor
    • Spondyloarthritis
    • Spondyloarthropathy
    • Sporadic colorectal cancer (SCRC)
    • Squamous cell carcinoma of bronchus or lung
    • Squamous cell carcinoma of cervix
    • Squamous cell carcinoma of oesophagus
    • Stable angina
    • Stable coronary artery disease (SCAD)
    • Stat3-Hyper-IgE syndrome
    • Stress-induced (Takotsubo) cardiomyopathy
    • Symptomatic cartilage defects
    • Synovial sarcoma
    • System indolent mastocytosis
    • Systemic lupus erythematosus
    • Thrombocytopenia
    • Thrombocytosis
    • Thyroid adenoma
    • Thyroid cancer
    • Thyroid carcinoma
    • Translocation-associated sarcoma
    • Traumatic ulcers
    • Tuberculosis
    • Ulcerative colitis
    • Undifferentiated arthritis
    • Unexplained recurrent anaphylaxis
    • Upper gastrointestinal cancers
    • UPS undifferentiated pleomorphic sarcoma
    • Urinary tract infection
    • Urticaria pigmentosa
    • Uterine cervical cancer
    • Vascular dementia
    • Viral meningoencephalitis
    • Wegener’s granuloma
    • Well-differentiated liposarcoma
    • Adenocarcinoma of oesophagus tumor tissue
    • Airway (bronchial) epithelium
    • Airway lamina propria
    • Airway smooth muscle
    • Airways adventitia
    • Airways basement membrane
    • Ascending colon lamina propria
    • Basement membrane of epidermis
    • Basement membrane of epidermis lesional
    • Basement membrane of epidermis nonlesional
    • Benign lung lesion homogenates
    • Blood
    • Blood arterial
    • Blood from tumor
    • Bone marrow
    • Bone marrow blood
    • Bone marrow plasma
    • Brain tissue lysate (BA21)
    • Breast cancer tumor tissue
    • Breast intra-ductal region
    • Breast intra-lobular region
    • Breast parenchyma
    • Breast peri-ductal region
    • Breast peri-lobular region
    • Breast peri-vascular region
    • Bronchial glands
    • Bronchial mucosa
    • Bronchial subepithelial tissue
    • Bronchial submucosa
    • Bronchial tissue
    • Bronchial wash
    • Bronchoalveolar carcinoma tumor tissue
    • Broncho-alveolar lavage (BAL)
    • Caecum mucosa
    • Cartilage
    • Cerebrospinal fluid (CSF)
    • Cervical tissue
    • Cervical tumor tissue
    • Colon
    • Colon epithelium
    • colon lamina propria lymphoid aggregates/solitary follicles
    • colon lamina propria outside lymphoid aggregates/solitary follicles
    • Colon mucosa
    • Colonic lamina propria
    • Colonic lymphoid follicles
    • Colorectal cancer tumor center
    • Colorectal cancer tumor invasive margin
    • Coproextracts
    • Dermis
    • Dermis papillary
    • Dermis papillary lesional
    • Dermis papillary nonlesional
    • Dermis upper
    • Dermis upper lesional
    • Dermis upper nonlesional
    • Descending colon mucosa
    • Distant metastasis
    • Duodenal lamina propria
    • Duodenal mucosa
    • Endobronchial (airway) biopsies
    • Epidermis
    • Epithelial lining fluid in airways
    • Esophageal cancer tumor tissue
    • Esophageal tumor tissue lysate
    • Exhaled Breath Condensate
    • Gastric tissue
    • Gastric tumor tissue
    • Gut-associated lymphoid tissue
    • Head and Neck Squamous Cell Carcinoma primary tumor
    • Hepatocellular carcinoma tumor tissue
    • Ileal mucosa
    • Ileum epithelium
    • Ileum lamina propria
    • Ileum/Colon mucosa
    • Induced Sputum
    • Inflamed caecum mucosa
    • Inflamed colon mucosa
    • Inflamed descending colon mucosa
    • Inflamed intestinal lamina propria
    • Inflamed left flexure mucosa
    • Inflamed rectum mucosa
    • Inflamed right flexure mucosa
    • Inflamed sigmoid colon mucosa
    • Intestinal granulomas
    • Intestinal lamina propria
    • Intestinal lymphoid aggregates
    • Intestinal mucosa
    • Intestinal mucosa lymphoid follicules
    • Intratumor soft tissue of synovial sarcoma
    • Intratumoral region of tumor-draining/sentinel lymph node - metastatic
    • Invasive margin of tumor soft tissue of synovial sarcoma
    • Left flexure mucosa
    • Lesional dermis
    • Lesional epidermis
    • Lesional skin
    • Liver
    • Liver metastases peritumoral
    • Liver metastasis intratumoral
    • Liver: hepatic lobules
    • Liver: portal area
    • Lung adenocarcinoma tumor tissue
    • Lung cancer tissue
    • Lung tissue
    • Lymph
    • Lymph node
    • Melanoma peritumoral tissue
    • Melanoma tumor tissue
    • Mesenteric lymph node
    • Metastasis in distant node
    • Metastasis in liver
    • Metastasis in lung
    • Metastasis in ovary
    • Non-inflamed intestinal lamina propria
    • Non-lesional dermis
    • Non-lesional epidermis
    • Non-lesional skin
    • NSCLC Intersection of tumor tissue and normal pulmonary tissue
    • NSCLC peritumoral tissue
    • NSCLC tissue (tumor+stroma)
    • NSCLC tumor islets (nests)
    • NSCLC tumor stroma
    • NSCLC tumor tissue
    • NSCLC Tumor tissue homogenate
    • Oesophageal adenocarcinoma tumor centre
    • Oesophageal adenocarcinoma tumor edge
    • Ovarian cancer tumor tissue
    • Palatine tonsils
    • Pancreatic tissue
    • Pancreatic tumor tissue
    • Pericardial effusion
    • Peripheral bronchial biopsy specimens
    • Peritoneum
    • Peritumoral region of tumor-draining/sentinel lymph node - metastatic
    • Peyer’s patches
    • Plasma
    • Plasma arterial
    • Plasma from cord blood
    • Pleural effusion
    • Rectum mucosa
    • Renal tissue
    • Renal tumor capsula
    • Renal tumor margin
    • Renal tumor stroma
    • Renal tumor tissue
    • Right flexure mucosa
    • Seeding metastasis
    • Serum
    • Serum from tumor
    • Sigmoid colon lamina propria
    • Sigmoid colon mucosa
    • Skin
    • Small intestine
    • Small intestine lamina propria
    • Spleen
    • Sputum
    • Squamous cell carcinoma tumor tissue
    • Stroma region of colon
    • Suction Blister Fluids
    • Synovial fluid
    • Synovial membrane
    • Synovial membrane intima
    • Synovial membrane subintima
    • Synovial membrane-around lymphocyte clusters
    • Synovial tissue
    • Thyroid adenoma tumor tissue
    • Thyroid carcinoma tumor tissue
    • Thyroid tissue
    • Transbronchial (alveolar tissue) biopsies
    • Tumor
    • Tumor region of colon
    • Tumor-draining/sentinel lymph node
    • Tumor-draining/sentinel lymph node - metastatic
    • Tumor-draining/sentinel lymph node - non-metastatic
    • Urine
    • 12-hydroxyeicosatetraenoic acid (12-HETE)
    • 15-hydroxyeicosatetraenoic acid (15-HETE)
    • 25-hydroxyvitamin D (25(OH)D)
    • 5-hydroxyeicosatetraenoic acid (5-HETE)
    • 6-Keto-Prostaglandin F1α (6-Keto-PGF1α)
    • 8-Hydroxy-2'-deoxyguanosine (8-OHdG)
    • 8-isoprostane
    • 9a,11b-Prostaglandin F2 (9a,11b-PGF2)
    • Abeta42
    • Adenosine deaminase (ADA)
    • Adiponectin
    • Adipsin
    • Adrenocorticotropic hormone (ACTH)
    • ALA (alpha-linolenic acid)
    • Alanine aminotransferase (ALT)
    • Albumin
    • ALP (Alkaline phosphatase)
    • Alpha-1 antitrypsin
    • Alpha1-fetoprotein
    • Alpha2-antiplasmin (A2PI)
    • Alpha2-macroglobulin (a2M)
    • Alpha-tocopherol
    • Amylase
    • Angiopoietin-2
    • Angiostatin
    • anti-HBc
    • Anti-SEA IgE (anti-staphylococcus enterotoxin A)
    • Anti-SEB IgE (anti-staphylococcus enterotoxin B)
    • ApoA-I
    • ApoA-II
    • ApoA-IV
    • ApoB
    • ApoC-III
    • ApoE
    • APRIL
    • Arachidonic Acid
    • Arginase I
    • Ascorbic acid
    • Aspartate aminotransferase (AST)
    • Axl (tyrosine-protein kinase 7)
    • BAFF
    • BAMBI
    • Beta-2-microglobulin
    • Betacellulin (BTC)
    • b-FGF (basic fibroblast growth factor, FGF2)
    • Bilirubin direct
    • Bilirubin indirect
    • Bilirubin total
    • Blood urea nitrogen
    • Brain natriuretic peptide (BNP)
    • Brain-derived neurotrophic factor (BDNF)
    • C1q (Complement component 1q)
    • C1s (Complement component 1s)
    • C1s inactivator
    • C2 (Complement component 2)
    • C3 (Complement component 3)
    • C3 PA (properdin factor B)
    • C3c (Complement component 3c)
    • C3d (Complement component 3d)
    • C4 (Complement component 4)
    • C9 (Complement component 9)
    • CA125 (cancer antigen 125)
    • CA12-5 (cancer antigen 12-5)
    • CA15-3 (cancer antigen 15-3)
    • CA19-9 (cancer antigen 19-9)
    • Carcinoembryonic antigen (CEA)
    • Cardiac Troponin I (cTnI)
    • Carotenoid
    • Cathelicidin (LL-37)
    • cccDNA
    • CCL1 [C-C motif chemokine Ligand 1]
    • CCL11
    • CCL13
    • CCL14 (HCC-1)
    • CCL15
    • CCL16 (HCC-4)
    • CCL17
    • CCL18
    • CCL19
    • CCL2
    • CCL20
    • CCL21
    • CCL22
    • CCL23
    • CCL24
    • CCL25
    • CCL26
    • CCL27 (CATCK)
    • CCL28
    • CCL3
    • CCL4
    • CCL5 [C-C motif chemokine Ligand 5]
    • CCL7
    • CCL8
    • CCP (Cyclic Citrullinated Peptide) antibodies
    • CGRP [Calcitonin Gene Related Protein]
    • Chitinase-3-like protein 1 (YKL-40)
    • Cholesterol
    • Cholesteryl ester
    • Cholinesterase (butyrylcholinesterase)
    • Citrate
    • CKMB (creatine kinase isoenzyme)
    • Collagen IV (C-IV)
    • Complement factor B
    • Cortisol
    • C-reactive protein (CRP)
    • Creatine kinase
    • Creatinine
    • CX3CL1
    • CXCL1
    • CXCL10
    • CXCL11
    • CXCL12
    • CXCL12a (SDF-1a)
    • CXCL13
    • CXCL16
    • CXCL2
    • CXCL4
    • CXCL5
    • CXCL6
    • CXCL7
    • CXCL9
    • CYFRA 21.1
    • Cystatin C (CysC)
    • Cysteinyl leukotrienes (Cys-LTs)
    • Cytokeratin18 (CK18)
    • D-dimer (fibrin degradation product)
    • DGLA (dihomo-gamma linolenic acid)
    • DHA (Docosahexaenoic acid)
    • DNAse1
    • DNAse1L3
    • DPA (Docosapentaenoic acid)
    • ECP [Eosinophil Cationic Protein]
    • Elafin
    • Elastin-derived peptide
    • EMMPRIN (CD147)
    • Endotoxin
    • Eosinophil protein Х (EPX)
    • EPA (Eicosapentaenoic acid)
    • Epidermal Growth Factor (EGF)
    • Fas
    • FasL
    • Ferritin
    • FGF
    • FGF-2 ( fibroblast growth factor 2)
    • Fibrin
    • Fibrin Degradation Products (FDP)
    • Fibrinogen
    • FLCs kappa
    • FLCs lambda
    • Flt3‑L
    • Follistatin
    • Free Choline
    • Free Fatty acids (FFA)
    • Free Glycerol
    • Gamma-globulin
    • gamma-Glutamyl Transpeptidase (GGT)
    • GCSF [Granulocyte Colony-Stimulating Factor]
    • GH (growth hormone/somatotropin)
    • Glial cell-derived neurotrophic factor (GDNF)
    • Globulin
    • Glucose
    • Glutathione peroxidase (GSH-PX)
    • Glycoprotein 130 (gp130)
    • Glycyl-proline-dipeptidyl aminopeptidase (GPDA)
    • GMCSF [Granulocyte-Macrophage Colony-Stimulating Factor]
    • GranzymeA
    • GranzymeB
    • Growth-related oncogene (GRO)
    • GSH (reduced glutathione)
    • GSSG (oxidised glutathione)
    • H2O2
    • Haptoglobin
    • hBD-2 (human β-defensin 2)
    • hBD-3 (human β-defensin 3)
    • HBeAg
    • HBsAg
    • HBV DNA
    • HBV RNA
    • HCV RNA
    • HDL-cholesterol
    • HDL-unesterified cholesterol
    • HE4 (Human epididymis protein 4)
    • Hemoglobin
    • Hepatocyte growth factor (HGF)
    • High mobility group box 1 (HMGB1, amphoterin)
    • high sensitive troponin I (hsTnI)
    • Hippurate
    • Histamine
    • HNPs (human neutrophil peptides, defensins)
    • Hyaluronic acid (HA)
    • ICAM
    • IFNa [Interferon Alpha]
    • IFNb
    • IFNg [Interferon gamma]
    • IgA
    • IgE
    • IGF-1 (insulin growth factor 1)
    • IGFBP-2 (insulin like growth factor binding protein 2)
    • IGFBP-3
    • IgG
    • IgG1
    • IgG2
    • IgG3
    • IgG4
    • IgM
    • IL1
    • IL10
    • IL11
    • IL12
    • IL12a (IL12p35)
    • IL12b (IL23p40)
    • IL12p70
    • IL13
    • IL15
    • IL16
    • IL17
    • IL17a
    • IL17af
    • IL17F
    • IL18
    • IL18 BPa
    • IL18BP (Interleukin-18 Binding Protein)
    • IL19
    • IL1a
    • IL1b
    • IL1RA [Interleukin-1 Receptor Antagonist]
    • IL1RAcP
    • IL1RL1 [Interleukin 1 Receptor Like 1]
    • IL2
    • IL20
    • IL21
    • IL22
    • IL23 (p19/p40)
    • IL23p19 (IL23a)
    • IL24
    • IL25
    • IL26
    • IL27
    • IL28a
    • IL29
    • IL2R
    • IL2Ra (CD25)
    • IL3
    • IL31
    • IL32
    • IL33
    • IL34
    • IL35
    • IL36
    • IL37
    • IL4
    • IL-41 (Meteorin-like)
    • IL5
    • IL6
    • IL7
    • IL8 [Interleukin 8]
    • IL9
    • Immune complexes (IC)
    • Immunoreactive LTC4 (iLTC4)
    • Insulin
    • Interferon (IFN)
    • Interferon Alpha 2 (IFNa2)
    • Iron
    • Keratinocyte growth factor
    • KL-6
    • Kynurenine
    • Lactate
    • Lactate dehydrogenase
    • Laminin (LN)
    • LDL-cholesterol
    • Leptin
    • LIF (leukemia inhibitory factor)
    • LIGHT (TNFSF14, CD258)
    • Linoleic Acid
    • Lipase
    • Lipocalin-2
    • LTB4
    • LTC4
    • LTD4
    • LTE4
    • Lysozyme
    • Mast cell chymase
    • Mast cell tryptase
    • MCSF
    • MDA (malondialdehyde)
    • MIF
    • MMP1
    • MMP10
    • MMP12
    • MMP13
    • MMP2
    • MMP3
    • MMP7
    • MMP8
    • MMP9
    • MSPa (macrophage stimulating protein a)
    • MUFA (Monounsaturated Fatty Acids)
    • Myeloperoxidase (MPO)
    • Myoglobin
    • Neopterin
    • Neurofilament light chain
    • Neuron-specifc enolase (NSE)
    • Neuropeptide Y
    • Neutrophil elastase
    • NGF [Nerve Growth Factor]
    • NGF-beta (beta-nerve growth factor)
    • NLRP3 (Nod-like receptor protein 3 inflammasome)
    • NO
    • Nonesterified Fatty Acid (NEFA)
    • Non-HDL-unesterified cholesterol
    • NT-proBNP (N-terminal brain natriuretic peptide)
    • Oleic Acid
    • Oncostatin-M
    • ONOO (Peroxynitrite)
    • Osteocalcin
    • Osteopontin (OPN)
    • PARC (recombinant human MIP-4)
    • PC-III (type III pre-collagen)
    • PDGF
    • PDGF-BB [Platelet Derived Growth Factor-BB]
    • PDGF-АА
    • Pentraxin-3
    • Perforin
    • Periostin
    • PGE1
    • PGE2 [Prostaglandin E2]
    • Phosphatidylcholine
    • PIIINP (procollagen-III N-terminal peptide)
    • Plasmin-alpha2-plasmin inhibitor complex (PIC)
    • Plasminogen
    • Plasminogen activator inhibitor-1 (PAI-1)
    • Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1)
    • Platelet-Activating Factor (PAF)
    • Pleiotrophin (PTN)
    • PlGF-1 (Placental growth Factor 1)
    • Prealbumin
    • pro-BNP (pro-B-type natriuretic peptide)
    • Procalcitonin
    • Procollagen-3
    • Prostaglandin D2
    • Prostaglandin F2b (PGF2b)
    • Prostaglandin F2α (PGF2α)
    • Protein carbonyls
    • Protein total
    • PSA (prostate‐specific antigen)
    • P-tau (phosphorylated tau)
    • PUFA (Polyunsaturated Fatty Acids)
    • Resistin
    • Retinol-binding protein (RBP)
    • RF (Rheumatoid Factor)
    • RF-IgM
    • RIPK1 (receptor-interacting protein kinase-1)
    • sAbetaPPbeta
    • sCD163
    • sCD23
    • sCD27
    • sCD30
    • sCD40L
    • SCGF-b (Stem Cell Growth Factor beta)
    • sc-kit (SCFR)
    • Secretory Leukocyte Protease Inhibitor (SLPI)
    • Selenium
    • Serum amyloid A
    • SFA (Saturated Fatty Acids)
    • Sgp130 (Soluble Glycoprotein 130)
    • sIL-18Ra
    • sIL1R1 (Soluble Interleukin-1 Receptor-1)
    • sIL1R2 (Soluble Interleukin-1 Receptor-2)
    • sIL1R3 (Soluble Interleukin-1 Receptor-3)
    • sIL1R4 (Soluble Interleukin-1 Receptor-4)
    • sIL2R
    • sIL2Ra (Soluble Interleukin-2 Receptor subunit alpha)
    • sIL6R
    • sIL7R
    • sILT3
    • SP-40,40 (clusterin)
    • Sphingomyelin
    • sP-selectin
    • Squamous cell carcinoma antigen (SCC)
    • sST2 (Soluble suppression of tumorigenicity-2)
    • Stem Cell Factor (SCF)
    • sTNF-R1
    • sTNF-R2
    • sTREM2 (soluble triggering receptor expressed on myeloid cells 2)
    • Substance P (SP)
    • SuperOxide Dismutase (SOD)
    • Surfactant protein A (SP-A)
    • Surfactant protein D (SP-D)
    • sVEGFR1
    • sVEGFR2
    • Taurine
    • TGFa
    • TGFb
    • TGFb1
    • TGFb1R1
    • TGFb1R2
    • TGFb2
    • TGFb3
    • Thioredoxin 1 (TRX1)
    • Thrombin-antithrombin complex (TAT)
    • Thrombopoietin (TPO, MGDF)
    • Thromboxane B2 (TXB2)
    • Thyroglobulin (TG)
    • Tim-3 (HAVCR2)
    • TIMP1
    • TIMP2
    • Tissue factor
    • Tissue Plasminogen Activator (tPA)
    • Tissue plasminogen activator (tPA)/plasminogen activator inhibitor type I (PAI) complex (tPA/PAI)
    • TL1A (TNFSF15)
    • TNFa
    • TNFb
    • TNFR1
    • TNTHSST (high-sensitivity troponin T)
    • Total bile acid (TBA)
    • Total cholesterol
    • TRAIL (TNF-related apoptosis-inducing ligand)
    • Transferrin
    • Triglyceride
    • Triglycerides
    • Troponin
    • Troponin I
    • Troponin T
    • Tryptase
    • TSLP
    • T-tau (total tau)
    • TWEAK
    • Unesterified cholesterol
    • Urate (Urea acid)
    • Urokinase-type plasminogen activator (uPA)
    • VAP-1 (vascular adhesion protein-1)
    • VCAM-1 (vascular cell adhesion molecule-1)
    • VEGF [Vascular Endothelial Growth Factor]
    • VEGF-A
    • VEGF-C
    • VEGF-D
    • VIP [Vasoactive Intestinal Peptide]
    • Vitamin A
    • XCL1
    • α-hydroxybutyrate dehydrogenase (α-HBDH)
    • α-L-fucosidase
    • Activated B-cells
    • Activated Eosinophils
    • Activated suppressor T cells
    • Activated Tc
    • Activated T-cells
    • Activated Th1
    • Activated switched memory B-cells
    • Antigen Presenting Cell (APC)
    • Apoptotic cells
    • Apoptotic eosinophils
    • Atypical memory B-cells
    • Basophils
    • B-cells
    • Bm1-cells
    • Bm2-cells
    • Bm3-cells
    • Bm4-cells
    • Bm5 Early cells
    • Bm5 Late cells
    • Breg cells
    • Cells
    • Central memory T-cells
    • Circulating tumor cells (CTCs)
    • Columnar epithelial cells
    • Dendritic Cells (DC)
    • Dermal dendritic cells
    • Double positive T cells (DP T cells)
    • Double-Negative B-cells
    • Double-negative T cells
    • Double-Positive (DP) memory Th-cells
    • Effector memory T-cells
    • Effector T-cells
    • Eosinophil
    • Epidermal cells
    • Epithelial cells
    • Fibroblast-like synoviocytes
    • Follicular Treg cells (Tfr)
    • gamma-delta T17-cells
    • gamma-delta T-cells
    • Germinal Center B-cells
    • Granulocytic Myeloid-Derived Suppressor Cells (G-MDSC)
    • Hepatocytes
    • Histiocytes
    • IDEC/IDDC
    • Immature B cells
    • Immature transitional B cells
    • Immune cells
    • Immunocytes(T-cells,B-cells,Mast cells)
    • Induced regulatory T cells
    • Inflammatory Dendritic Epidermal Cells (IDEC)
    • Innate lymphoid cells 2 (CRTH2+)
    • Invariant natural killer T-cell
    • Kupffer cells
    • Langerhans Cells (LC)
    • Lymph node-resident Dendritic cell (LNDC)
    • Lymphocytes
    • Macrophages
    • Mast cells
    • Mast cells progenitor
    • Mature B cells
    • Mature Dendritic Cells (DC)
    • Mature Langerhans cells
    • Memory B-cells
    • Memory regulatory T-cells
    • Memory Tc-cells
    • Memory T-cells
    • memory Th17.1-cells
    • memory Th17-cells
    • Memory Th1-cell
    • memory Th22-cells
    • memory Th2-cells
    • memory Th-cells
    • Metachromatic cells (mast cells and basophils)
    • Monocytes
    • Monocytes/macrophages
    • Monocytic Myeloid-Derived Suppressor Cells (M-MDSC)
    • Mononuclear cells
    • Myeloid cells
    • Myeloid Dendritic Cells (mDC)
    • Myeloid Dendritic Cells 1 (mDC1)
    • Myeloid Dendritic Cells 2 (mDC2)
    • Myeloid-Derived Suppressor Cells (MDSC)
    • Naive B-cells
    • Naive regulatory T-cells
    • Naive suppressor T cells
    • Naive Tc-cell
    • Naive T-cells
    • Naive Th1
    • Naive Th-cells
    • Natural Effector B-cells
    • Natural killer T-cells
    • Neutrophil
    • Neutrophil total
    • Neutrophils Nonsegmented
    • Neutrophils Segmented
    • NK [Natural Killer cells]
    • NK1
    • NK17
    • NK2
    • NKT [Natural Killer-like T-cells]
    • Non-memory B cells
    • Non‐switched memory B-cells
    • Pan-leukocytes
    • PBMC (Lymphocytes and Monocytes)
    • PD-L1+ Cell
    • Peripheral blood monocytes
    • Peripheral blood mononuclear MDSCs (PMN-MDSCs)
    • Plasma B-cells
    • Plasmablasts
    • Plasmacytoid Dendritic Cells (pDC)
    • Platelets
    • Polymorphonuclear (PMN) leukocytes (granolocytes)
    • Precursor neutrophils
    • Precursor of Germinal Center B-cells
    • Red blood cells
    • Resting class-switched memory B-cells
    • Resting neutrophils
    • Sensory Nerve Endings
    • Squamous cells
    • Stem Cell Memory T cell (Tscm)
    • Suppressor T cells
    • Suppressor T-lymphocytes
    • Switched memory B-cells
    • Tc17-cell
    • Tc1-cell
    • Tc22-cell
    • Tc2-cell
    • Tc9-cell
    • Tc-cells
    • T-cells
    • Tconv cells
    • Tcreg-cells
    • Teff/Treg cell
    • Terminally differentiated effector T cells (EMRA)
    • Tfh17-cells
    • Tfh1-cells
    • Tfh2-cells
    • Tfh-cells (follicular helper T-cells)
    • Th0-cells
    • Th17.1-cells
    • Th17-cells
    • Th1-cells
    • Th22-cells
    • Th2-cells
    • Th9-cells
    • Th-activated
    • Th-cells
    • Th-cells exhausted
    • T-helper lymphocytes
    • TIP-DC (TNF and iNOS-producing dendritic cell)
    • Total cell count
    • Tph-cells (peripheral helper T-cells)
    • Transitional B cells
    • Treg-cells
    • Trm-cells (tissue-resident memory T cells)
    • White Blood Cells (WBC)
  • 32163 values of cytokine/cell concentrations;
  • data extracted from 915 papers/other public sources.

CYTOCON DB is developed as a web application based on the ASP.NET MVC framework. It works under Microsoft IIS web server. The data warehouse is a Microsoft SQL Server database. The user interface application is implemented using Telerik Kendo UI and Bootstrap.

Versions of the database:

    Commercial version entitled as “CYTOCON DB”

    Public version entitled as “CYTOCON DB Open”

CYTOCON DB 

    CYTOCON DB is a version of the database which is accessible via purchasing the commercial license

    To arrange the purchase, please contact us by email: support@insysbio.com  

    Both content and functionality of CYTOCON DB is described above and updated on the monthly basis (approximately 1500 cell/molecule concentrations per month)  

CYTOCON DB Open version

    CYTOCON DB Open is a version of the database which is accessible for public use

    To access CYTOCON DB Open, please visit www.cytocon-open.insysbio.com 

    CYTOCON DB Open has the same functionality as CYTOCON DB

    Content of CYTOCON DB Open is described at www.cytocon-open.insysbio.com  

    Both content and functionality of CYTOCON DB Open will be updated once per year

e-mail for correspondence: support@insysbio.com