openapi: 3.0.3 info: title: CYTOCON API description: | This API allows access to **CYTOCON DB** (**C**ell and c**YTO**kine**CON**centrations **D**ata**B**ase), a manually curated online database containing baseline of cells and cytokines concentrations in different tissues of both healthy individuals and patients suffering from various pathologies. **Important!** In order to make a query, all parameters must be chosen from the database dictionaries. termsOfService: https://cytocon-open.insysbio.com/TermOfUse contact: email: support@insysbio.com license: name: Apache 2.0 url: http://www.apache.org/licenses/LICENSE-2.0.html version: 1.0.0 externalDocs: description: Find out more about CYTOCON url: https://cytocon.insysbio.com/Index.aspx servers: - url: https://cytocon.insysbio.com/api/v1 tags: - name: diseases description: List of disease names - name: tissues_types description: Tissues types - name: species description: Species types - name: markers description: Cells markers - name: patient_group_attributes description: Patient groups attributes - name: disease_attributes description: Disease attributes - name: query_data description: Query result data - name: query_data_headers description: Query headers data paths: /diseases: get: tags: - diseases summary: | Return full list of the diseases to be used in Query (optional parameter for query). responses: '200': description: successful operation content: application/json: schema: type: array items: $ref: '#/components/schemas/Disease' '400': description: Invalid status value. This response appears when the required object does not exist in the DB. security: - cytocon_auth: - read:diseases /tissues_types: get: tags: - tissues_types summary: | Return list of tissue types (compartments where cells or molecules measured) to be used in Query (optional parameter for query). responses: '200': description: successful operation content: application/json: schema: type: array items: $ref: '#/components/schemas/TissueType' '400': description: Invalid status value. This response appears when the required object does not exist in the DB. security: - cytocon_auth: - read:tissues_types /species: get: tags: - species summary: | Return list of Species (names for cells and molecules) to be used in Query (mandatory parameter for query). responses: '200': description: successful operation content: application/json: schema: type: array items: $ref: '#/components/schemas/Species' '400': description: Invalid status value. This response appears when the required object does not exist in the DB. security: - cytocon_auth: - read:species /markers: get: tags: - markers summary: | Return list of Markers to be used in Query (optional parameter for query). Users can refine searches for cell concentrations by specifying cell markers (e.g. CD4+ and IL4+ for T-helper type 2 cells). responses: '200': description: successful operation content: application/json: schema: type: array items: $ref: '#/components/schemas/Marker' '400': description: Invalid status value. This response appears when the required object does not exist in the DB. security: - cytocon_auth: - read:marker /patient_group_attributes: get: tags: - patient_group_attributes summary: | Return list of patient group attributes. Required for query result output. The results of queries may include demographic information such as age, race, gender, and other details, such as the number of patients in the study, if the source provides such information. responses: '200': description: successful operation content: application/json: schema: type: array items: $ref: '#/components/schemas/PatientGroupAttribute' '400': description: Invalid status value. This response appears when the required object does not exist in the DB. security: - cytocon_auth: - read:patient_group_attributes /disease_attributes: get: tags: - disease_attributes summary: | Return list of Disease attributes. Required for query result output. The results of queries may include disease-specific clinical measures, e.g. Forced Expiratory Volume (FEV1) for Asthma; SLEDAI 2K range, interferon signature for Systemic Lupus Erythematosus (SLE); SCORAD range, severity, IgE concentration range for Atopic Dermatitis. responses: '200': description: successful operation content: application/json: schema: type: array items: $ref: '#/components/schemas/DiseaseAttribute' '400': description: Invalid status value. This response appears when the required object does not exist in the DB. security: - cytocon_auth: - read:disease_attributes /query_data_headers: get: parameters: - name: diseases in: query description: 'list of diseases names separated by "," choosed query list. "OR" logical operator' schema: type: string tags: - query_data_headers summary: | Return list with query header output according to parameters provided. There one parameter, where "Diseases" is optional. Multiple inputs can be selected, but currently, only the "OR" logic is supported. responses: '200': description: successful operation content: application/json: schema: type: array items: $ref: '#/components/schemas/QueryDataHeader' '400': description: Invalid status value. This response appears when the required object does not exist in the DB. security: - cytocon_auth: - read:query_data_headers /query_data: get: parameters: - name: species in: query description: 'list of species names separated by "," choosed species list. "OR" logical operator' required: true schema: type: string - name: tissue_types in: query description: 'list of tissues names separated by "," choosed tissue_types list. "OR" logical operator' schema: type: string - name: diseases in: query description: 'list of diseases names separated by "," choosed query list. "OR" logical operator' schema: type: string - name: markers in: query description: 'list of markers names separated by "," choosed markers list. "OR" logical operator' schema: type: string - name: wstatSwitch in: query description: 'true - only weighted result or false - all data without weighted result' schema: type: string - name: headers in: query description: 'comma separated list of params to output to result' schema: type: string tags: - query_data summary: | Return list with query output according to parameters provided. There are a total of four parameters, where "Species" is mandatory, and "Tissue types", "Diseases", and "Cell markers" are optional. Multiple inputs can be selected for all parameters, but currently, only the "OR" logic is supported. responses: '200': description: successful operation content: application/json: schema: type: array items: $ref: '#/components/schemas/QueryData' '400': description: Invalid status value. This response appears when the required object does not exist in the DB. security: - cytocon_auth: - read:query_data components: schemas: Disease: required: - name - id type: object properties: id: type: integer format: int64 example: 10 name: type: string example: Asthma description: Disease name available TissueType: required: - name - id type: object properties: id: type: integer format: int64 example: 10 name: type: string description: Tissue name available example: Lymph node Species: required: - name - id type: object properties: id: type: integer format: int64 example: 10 name: type: string description: Species name available example: T-cells Marker: required: - name - id type: object properties: id: type: integer format: int64 example: 10 name: type: string description: Cells marker available example: CD4+ PatientGroupAttribute: required: - name - id type: object properties: id: type: integer format: int64 example: 10 name: type: string description: Patient group name used example: Patient number DiseaseAttribute: required: - name - id type: object properties: id: type: integer format: int64 example: 10 name: type: string description: Disease attribute name used example: Cancer stage (I-IV) QueryDataHeader: type: object properties: ColumnVariable: type: string description: 'column variable name' ColumnDesc: type: string description: 'column description' QueryData: required: - s_name - s_val - u_base type: object properties: s_name: type: string description: Species name (Cell or molecule names) example: T-cells s_unf_val: type: number format: double description: Species value arithmetic mean (Concentration in unified form of avarage in database. Dimension in pM or k cell/L) example: 1498528.0 s_disp_unf: type: number format: double description: Species standard deviation (Unified form of dispersion in database. Dimension in pM or k cell/L) example: 190396.0 markers: type: string description: Cell markers (List of markers associated with cells) example: CD3+ s_val: type: number format: double description: Species value (Concentration in unified units. Dimension in pM or k cell/L) example: 1498528.0 s_val_isf: type: number format: double description: Species value in ISF (Concentration in unified units (pM or kcell/L) recalculated regarded interstitial fluid volume) example: 111.1 s_disp_left: type: number format: double description: Species dispersion left (Left border in unified units. Dimension in pM or k cell/L) example: 60208.0 s_disp_right: type: number format: double description: Species dispersion right (Right border in unified units. Dimension in pM or k cell/L) example: 15.0 s_disp_min: type: number format: double description: Species min value (Minimum value in unified units. Dimension in pM or k cell/L) example: 17.0 s_disp_max: type: number format: double description: Species max value (Maximum value in unified units. Dimension in pM or k cell/L) example: 12.0 s_val_org: type: number format: double description: Species value (original). Original value from source example: 67.2 s_disp_left_org: type: number format: double description: Species dispersion left(original). Original value from source example: 2.7 s_disp_right_org: type: number format: double description: Species dispersion right(original). Original value from source example: 12.7 s_disp_min_org: type: number format: double description: Species min value(original). Original value from source example: 1.66 s_disp_max_org: type: number format: double description: Species max value(original). Original value from source example: 12.5 u_base: type: string description: Unified units (pM or kcell/L) example: kcells/L u_org: type: string description: Original unit (unit from source) example: '%__Lymphocytes_Blood_Atopic dermatitis' u_rcl_ass: type: string description: Recalculation assumptions. If we recalculate the original value (e.g. due to a misprint in the paper or when we need calculate exact number from % using external data), we explicitly explain how and why the recalculation was performed example: Exact number calculated from % using averaged concentration of the maternal cell in the tissue and the disease from CYTOCON DB data tissue_t: type: string description: Tissue type example: Blood disease: type: string description: Disease example: Atopic dermatitis avg_t: type: string description: Average type example: Mean disp_t: type: string description: Dispersion type example: SEM exp_m: type: string description: Experimental method example: FACS (Fluorescence-activated cell sorting) id_type: type: string description: ID type (ID for original source (e.g. PMID)) example: PMID id_val: type: string description: ID value example: 15932386 link: type: string description: Link to place in paper where value was found example: Table 2, p.949 source: type: string description: Source type (e.g paper, book, etc.) example: Article pg_desc: type: string description: Patient group description example: All patients suffered from an acute exacerbation of their AD and were treated with pimecrolimus cream 1% twice daily for 3 weeks pg_sg: type: string description: Patient group is subgroup. If a value is extracted in addition to the overall value from a large cohort (e.g., the paper presents data for all patients, then divides it by males and females), we indicate this example: No has_misprint: type: string description: If we detect a misprint (e.g., incorrect dimensions), we indicate it example: No sv_desc: type: string description: Species values description (additional information that can be useful for users about this value) example: NA pgAttr1: type: string format: string description: 'race/ethnicity or group of races of patients' pgAttr2: type: integer format: int32 description: 'number of males in patient group' pgAttr3: type: integer format: int32 description: 'number of females in patient group' pgAttr4: type: number format: double description: 'Average age of the patient group' pgAttr10: type: string format: string description: 'any other attributes of patient group' pgAttr11: type: integer format: int32 description: 'Patient number in the group' pgAttr15: type: number format: double description: 'Patient weight in kg' pgAttr16: type: number format: double description: 'Patient BMI (body mass index) in kg/m2' pgAttr17: type: number format: double description: 'Patient group average height' pgAttr18: type: string format: string description: 'Patient Smoking status' pgAttr21: type: number format: double description: 'Fasting before blood draw (hours)' pgAttr22: type: string format: string description: 'Exclusion criteria for patient group' pgAttr23: type: string format: string description: 'Inclusion criteria for patients' pgAttr24: type: string format: string description: 'Information about treatment' pgAttr25: type: string format: string description: 'additional diagnoses' pgAttr26: type: integer format: int32 description: 'Samples number of the patient group' pgAttr27: type: string format: string description: 'Patient drinking history' pgAttr28: type: string format: string description: 'Alcohol history' pgAttr29: type: number format: double description: 'Waist-Hip Ratio (WHR)' pgAttr30: type: number format: double description: 'Erythrocyte sedimentation rate' pgAttr31: type: string format: string description: 'blood groups' pgAttr32: type: number format: double description: 'Waist circumference i.e. for patients with diabet' dsAttr1: type: number format: double description: 'SCORing Atopic Dermatitis' dsAttr4: type: string format: string description: 'Severity of the disease' dsAttr7: type: string format: string description: 'Atopic dermatitis type' dsAttr8: type: string format: string description: 'Atopic dermatitis phase' dsAttr14: type: number format: double description: 'Forced expiratory volume in 1 second, spirometry characteristic' dsAttr15: type: string format: string description: 'Global initiative for chronic Obstructive Lung Disease (GOLD) criteria' dsAttr16: type: string format: string description: 'High/Low level of IFN1 gene expression' dsAttr17: type: number format: double description: 'SLEDAI 2K score' dsAttr18: type: number format: double description: 'Glucocorticosteroids dose' dsAttr19: type: number format: double description: 'Glucocorticosteroids dose' dsAttr20: type: number format: double description: 'Immunoglobulin E specific concentration' dsAttr21: type: number format: double description: 'Immunoglobulin E total concentration' dsAttr25: type: string format: string description: 'Active/inactive stage of the disease' dsAttr26: type: string format: string description: 'Cancer stage (I-IV)' dsAttr27: type: string format: string description: 'T stage of cancer (TNM)' dsAttr28: type: string format: string description: 'N stage of cancer (TNM)' dsAttr29: type: string format: string description: 'M stage of cancer (TNM)' dsAttr30: type: number format: double description: 'peak expiratory flow' dsAttr31: type: number format: double description: 'fraction of exhaled NO' dsAttr33: type: integer format: int32 description: 'Number of patients using prescribed ICS regularly and properly' dsAttr34: type: number format: double description: 'Daily dose of ICS' dsAttr35: type: number format: double description: 'airway resistance' dsAttr36: type: integer format: int32 description: 'Crohn’s Disease Activity Index (CDAI)' dsAttr37: type: number format: double description: 'Disease duration' dsAttr55: type: number format: double description: 'objective SCORAD' dsAttr56: type: number format: double description: 'TEWL g/m2/h' dsAttr57: type: number format: double description: 'Pruritus score' dsAttr58: type: number format: double description: 'Sleep loss' dsAttr59: type: number format: double description: 'Extent (%) - affected Body Surface Area (BSA)' dsAttr60: type: number format: double description: 'CDLQI - Children’s Dermatology Life Quality Index' dsAttr61: type: number format: double description: 'SH (Skin Hydration) measured on Corneometer CM 825' dsAttr62: type: number format: double description: 'FEV1 % of the patient divided by the average FEV1% in the population for any person of similar age, sex, and body composition' dsAttr63: type: number format: double description: '% reversibility of asthma' dsAttr64: type: number format: double description: 'Provocation concentration (PC) that results in a 20% fall in the forced expiratory volume in 1 second (FEV1)' dsAttr65: type: number format: double description: 'The provocative dose of methacholine causing a ≥20% fall in FEV1 (PD20)' dsAttr66: type: number format: double description: 'Wheal diameter induced by allergen (mm)' dsAttr67: type: string format: string description: 'Status asthmaticus existence' dsAttr68: type: number format: double description: 'FEV1 before salbutamol (% predicted)' dsAttr69: type: number format: double description: 'FEV1 after salbutamol (% predicted)' dsAttr70: type: string format: string description: 'Astma severity score' dsAttr71: type: number format: double description: 'for PMID 24800011' dsAttr72: type: number format: double description: 'Psoriasis Area Severity Index' dsAttr73: type: number format: double description: 'System developed and validated by the EULAR to measure the progress and improvement of Rheumatoid Arthritis' dsAttr74: type: string format: string description: 'Severity score for acute allergic reactions' dsAttr75: type: string format: string description: 'Cancer stage for mixed groups' dsAttr76: type: string format: string description: 'Tumor histological grade' dsAttr77: type: string format: string description: 'Sarcoidosis stages (chest radiograph stages (Scadding criteria))' dsAttr78: type: string format: string description: 'Performance status (Eastern Cooperative Oncology Group)' dsAttr79: type: string format: string description: 'Harvey–Bradshaw Index' dsAttr80: type: string format: string description: 'Endoscopic activity score (Rutgeerts)' dsAttr81: type: string format: string description: 'Clinical activity index (Mayo)' dsAttr82: type: string format: string description: 'Endoscopic activity score (Mayo)' dsAttr83: type: string format: string description: 'Clark''s level is a staging system, which describes the level of anatomical invasion of the melanoma in the skin' dsAttr84: type: number format: double description: 'Systemic Lupus Erythematosus Disease Activity Index' dsAttr85: type: number format: double description: 'Systemic Lupus International Collaborating Clinics/ACR Damage Index; SDI' dsAttr86: type: number format: double description: 'Anti-dsDNA: anti-double-stranded DNA' dsAttr87: type: number format: double description: 'Mini Mental State Examination (MMSE) score' dsAttr88: type: number format: double description: 'SLE disease activity score [ECLAM]' dsAttr89: type: number format: double description: 'APOE E4 carrier or non-carrier (% of patients))' dsAttr90: type: string format: string description: 'ISN/RPS (International Society of Nephrology/Renal Pathology Society) class' dsAttr91: type: number format: double description: 'chronicity index (CI)' dsAttr92: type: number format: double description: 'Expanded Disability Status score' dsAttr93: type: string format: string description: 'W.H.O. grade of cancer' dsAttr94: type: number format: double description: 'Systemic Lupus Activity Measure (SLAM)' dsAttr95: type: string format: string description: 'compensated and decompensated phases' dsAttr96: type: number format: double description: 'Histological activity index for hepatitis' dsAttr97: type: string format: string description: 'Period of infection disease' dsAttr98: type: string format: string description: 'Fibrosis stage for hepatitis B' dsAttr99: type: string format: string description: 'Inflammation grade for chronic hepatitis B' dsAttr100: type: number format: double description: 'for chronic hepatitis B' dsAttr101: type: number format: double description: 'for chronic hepatitis B' dsAttr102: type: number format: double description: 'Anti-dsDNA/reference anti-dsDNA ratio' dsAttr103: type: number format: double description: 'Necroinflammation grading for CHB' dsAttr104: type: string format: string description: 'Hepatitis B e antigen seropositivity' dsAttr105: type: string format: string description: 'hepatitis B core antigen Expression Patterns in Hepatocyte' dsAttr106: type: string format: string description: 'HBsAg Expression Patterns in Hepatocyte' dsAttr107: type: number format: double description: 'For hepatitis' dsAttr108: type: string format: string description: 'HBsAg seropositivity' dsAttr109: type: string format: string description: 'Glomerulonephritis class I-V' dsAttr110: type: number format: double description: 'For Lupus nephritis was added' dsAttr111: type: string format: string description: 'For IgA nephropathy' dsAttr112: type: string format: string description: 'parenchymal liver disease (PLD) score' dsAttr113: type: string format: string description: 'a system for assessing the prognosis of chronic liver disease, primarily cirrhosis' dsAttr114: type: number format: double description: 'Clinical dementia rating (CDR)' dsAttr115: type: string format: string description: 'Activity of inflammation for chronic hepatitis B' dsAttr116: type: string format: string description: 'Hepatitis C Virus genotype' dsAttr117: type: string format: string description: 'Hepatitis B Virus genotype' dsAttr118: type: string format: string description: 'International Federation of Gynecology and Obstetrics clinical stage for uteric cervical cancer' dsAttr119: type: string format: string description: 'Tumor differentiation status' dsAttr120: type: string format: string description: 'Lymph node metastasis existence' dsAttr121: type: string format: string description: 'For Uterine cervical cancer' dsAttr122: type: string format: string description: 'Cancer vasoinvasion existence' dsAttr124: type: string format: string description: 'Human papillomavirus positive/negative' dsAttr125: type: string format: string description: 'Larsen grade value' dsAttr126: type: string format: string description: 'anti-CCP antibody in plasma' dsAttr127: type: string format: string description: 'Anti-HBe antigen in serum for chronic hepatitis B' dsAttr128: type: string format: string description: 'for chronic hepatitis C, HCV-DNA in blood' dsAttr129: type: number format: double description: 'for Rheumatoid arthritis' dsAttr130: type: string format: string description: 'Kellgren-Lawrence grading scale' dsAttr131: type: string format: string description: 'for Rheumatoid arthritis according to DAS28' dsAttr132: type: string format: string description: 'Rheumatoid factor (RF) seropositivity' dsAttr133: type: number format: double description: 'for Rheumatoid arthritis' dsAttr134: type: number format: double description: 'Percent of Non-survivors (i.e. for COVID-19)' dsAttr135: type: number format: double description: 'For Ulderative colitis according to Lichtiger' dsAttr136: type: string format: string description: 'Marburg cancer stage or SCLC' dsAttr137: type: string format: string description: 'For Crohn''s disease' dsAttr138: type: number format: double description: 'Crohn’s Disease Endoscopic Index of Severity (CDEIS)' dsAttr139: type: string format: string description: 'Oral lichen planus type' dsAttr140: type: string format: string description: 'Tumor histology type' dsAttr141: type: string format: string description: 'Her2 expression i.e. for breast cancer' dsAttr142: type: string format: string description: 'Lymphovascular space invasion existence i.e. for Cervical cancer' dsAttr143: type: string format: string description: 'for colorectal cancer' dsAttr144: type: string format: string description: 'Progesteron receptor expression on tumor cells (for breast cancer)' dsAttr145: type: string format: string description: 'Estrogen receptor status for breast cancer' dsAttr146: type: string format: string description: 'Simple Endoscopy Severity' dsAttr147: type: string format: string description: 'Global Initiative for Asthma (GINA)' dsAttr148: type: number format: double description: 'recommended by GINA' dsAttr149: type: string format: string description: 'the tendency to produce an exaggerated IgE immune response to otherwise harmless substances in the environment' dsAttr150: type: number format: double description: 'Harvey-Bradshaw Index' dsAttr151: type: string format: string description: 'Endoscopic severity (Mayo)' dsAttr152: type: number format: double description: 'Positive and Negative Syndrome Scale (PANSS) for schizophrenia' dsAttr153: type: number format: double description: 'severity of depressive symptoms' dsAttr154: type: number format: double description: 'Acute Physiology and Chronic Health Evaluation' dsAttr155: type: string format: string description: 'for HCC' dsAttr156: type: string format: string description: 'Distant metastasis existence, i.e. extrahepatic metastasis for HCC' dsAttr157: type: string format: string description: 'for arthritis' dsAttr158: type: string format: string description: 'Antinuclear antibody (ANA)-seropositivity i.e. for arthritis' dsAttr159: type: string format: string description: 'HLA-B27 seropositivity i.e. for arthritis' dsAttr160: type: string format: string description: 'American Society of Reproductive Medicine (ASRM) classification of endometriosis' dsAttr161: type: string format: string description: 'Phase of the menstrual cycle' dsAttr162: type: string format: string description: 'For prostate cancer' dsAttr163: type: number format: double description: 'The Behcet’s Disease Current Activity Form (BDCAF) transformed index' dsAttr164: type: number format: double description: 'PSI, pneumonia severity index' dsAttr165: type: number format: double description: 'SOFA, Sepsis-related organ failure assessment score' dsAttr166: type: number format: double description: 'SAPS, simplified acute physiology score' dsAttr167: type: string format: string description: 'For Lymphoma' dsAttr168: type: string format: string description: 'For Lymphoma' dsAttr169: type: string format: string description: 'For Lymphoma' dsAttr170: type: number format: double description: 'PCDAI = pediatric Crohn''s disease activity index' dsAttr171: type: number format: double description: 'PUCAI = pediatric ulcerative colitis activity index' dsAttr172: type: string format: string description: 'For Hodgkin''s Lymphoma' dsAttr173: type: string format: string description: 'For Lymphoma' dsAttr174: type: string format: string description: 'For Lymphoma' dsAttr175: type: string format: string description: 'Clinical outcome of the disease' dsAttr176: type: number format: double description: 'For diabets, glycated hemoglobin' dsAttr177: type: number format: double description: 'for COVID-19' dsAttr178: type: number format: double description: 'for IBD' dsAttr179: type: string format: string description: 'For UC' dsAttr180: type: number format: double description: 'for UC' dsAttr181: type: number format: double description: 'Simple endoscopic score for CD' dsAttr182: type: number format: double description: 'For CD' dsAttr183: type: string format: string description: 'for NSCLC' dsAttr184: type: number format: double description: 'for disease severity PMID32979941,p.e3' dsAttr185: type: number format: double description: 'Tumor size (cm)' dsAttr186: type: string format: string description: 'Tumor Infiltrating Lymphocytes PD-L1 expression (for breast cancer)' dsAttr187: type: string format: string description: 'Tumor cell PD-L1 expression (for breast cancer)' dsAttr188: type: string format: string description: 'For AML, French-American-British (FAB) classification system is based on morphology to define specific immunotypes' dsAttr189: type: string format: string description: 'St Gallen 2015 International Expert Consensus for Breast cancer' dsAttr190: type: number format: double description: 'DASO (Days after symptom onset)' dsAttr191: type: number format: double description: 'for COVID-19' dsAttr192: type: number format: double description: 'Breslow thickness is the measurement of the depth of the melanoma from the surface of your skin down through to the deepest poin' dsAttr193: type: number format: double description: 'for COVID-19' dsAttr194: type: number format: double description: 'for MDS' dsAttr195: type: number format: double description: 'Hamilton depression rating scale, without suicide ideation item' dsAttr196: type: number format: double description: 'Buss Perry aggression questionnaire' dsAttr197: type: number format: double description: 'for COVID-19' dsAttr198: type: number format: double description: 'qSOFA, quick Sequential Organ Failure Assessment' dsAttr199: type: number format: double description: 'CMI, Charlson Comorbidity Index' dsAttr200: type: string format: string description: 'anti-HBs seropositivity' dsAttr201: type: number format: double description: 'Model for end-stage liver disease (MELD) scores' dsAttr202: type: string format: string description: 'HBc-antibody seropositivity' dsAttr203: type: string format: string description: 'for COVID-19' dsAttr204: type: string format: string description: 'for Multiple sclerosis and others' dsAttr205: type: string format: string description: 'for Multiple sclerosis' dsAttr206: type: number format: double description: 'Aneurysmal diameter' dsAttr207: type: number format: double description: 'for aneurysma' dsAttr208: type: number format: double description: 'for strokes' dsAttr209: type: number format: double description: 'a cumulative and weighted index used to assess disease activity across 24 different disease descriptors in patients with SLE' dsAttr210: type: number format: double description: 'measures the overall response to treatment as assessed by the physician' dsAttr211: type: number format: double description: 'for COVID-19' dsAttr212: type: string format: string description: 'for Multiple myeloma' dsAttr213: type: string format: string description: 'for Multiple myeloma' dsAttr214: type: string format: string description: 'ECOG Eastern Cooperative Oncology Group' dsAttr215: type: number format: double description: 'alpha smooth muscle actin - for Pancreatic cancer' dsAttr216: type: number format: double description: 'For Pancreatic cancer' dsAttr217: type: string format: string description: 'HCV-Ab seropositivity' dsAttr218: type: string format: string description: 'for HCC' dsAttr219: type: string format: string description: 'BCLC stage, the Barcelona Clinic Liver Cancer stage' dsAttr220: type: number format: double description: 'a method for assessing β-cell function and insulin resistance (IR) from basal (fasting) glucose and insulin or C-peptide concent' dsAttr221: type: string format: string description: 'for HCC' dsAttr222: type: string format: string description: 'bleeding scale ' dsAttr223: type: string format: string description: 'for HCC' dsAttr224: type: number format: double description: 'estimating the risk of short-term mortality from actual clinical data in the first day after admission' dsAttr225: type: string format: string description: 'Bone Lesion Score' dsAttr226: type: string format: string description: '(positive/negative)' dsAttr227: type: string format: string description: 'for Gastric cancer' dsAttr228: type: string format: string description: 'for Crohn Disease' dsAttr229: type: string format: string description: 'for Crohn disease' dsAttr230: type: string format: string description: 'for Crohn Disease' dsAttr231: type: string format: string description: 'Stage 1: Infection ; Stage 2: Asymptomatic ; Stage 3: Symptomatic ; Stage 4: AIDS/Progression of HIV to AIDS.' dsAttr232: type: number format: double description: 'Forced Ventilatory Capacity' dsAttr233: type: number format: double description: 'Total Lung Capacity' dsAttr234: type: number format: double description: 'Diffusion capacity of the Lung for Carbon monoxide corrected for hemoglobin level' dsAttr235: type: number format: double description: 'Disease Activity Score 28 joints combined with CRP value' dsAttr236: type: number format: double description: 'for Multiple sclerosis - an MS relapse, flare-up, or exacerbation' dsAttr237: type: string format: string description: 'for coeliac disease' dsAttr238: type: string format: string description: 'for Coeliac disease' dsAttr239: type: string format: string description: 'Kirsten rat sarcoma viral oncogene homologue (KRAS) is the best-known oncogene' dsAttr240: type: string format: string description: 'EGFR mutation' dsAttr241: type: string format: string description: 'Tumor location' dsAttr242: type: string format: string description: 'Marsh Classification of histologic findings in celiac disease (Oberhuber)' dsAttr243: type: number format: double description: 'For RA and PsA' dsAttr244: type: number format: double description: 'For RA and PsA' dsAttr245: type: number format: double description: 'Larsen score for RA (0–4)' dsAttr246: type: number format: double description: 'Radiological score of sacroileitis for PsA (0–4)' dsAttr247: type: number format: double description: 'BASDAI Bath Ankylosing Spondylitis Disease Activity Index' dsAttr248: type: number format: double description: 'MASES Maastricht Ankylosing Spondylitis Enthesitis Score' dsAttr249: type: string format: string description: 'For COPD' dsAttr250: type: number format: double description: 'MSSS (multiple sclerosis severity score)' dsAttr251: type: number format: double description: 'TJC68' dsAttr252: type: number format: double description: 'SJC66' dsAttr253: type: number format: double description: 'MRss, modified Rodnan skin score' dsAttr254: type: string format: string description: 'the sum of the size of the largest tumor in cm and the total number of tumors in the absence of tumor microvascular invasion.' dsAttr255: type: string format: string description: 'the small number of cancer cells in the body after cancer treatment. An MRD positive test result means that disease was still de' dsAttr256: type: number format: double description: 'Multiple Sclerosis Impact Scale 29' dsAttr257: type: number format: double description: 'Multiple Sclerosis Impact Scale 29,' dsAttr258: type: number format: double description: 'Symbol Digit Modalities Test' dsAttr259: type: string format: string description: 'Ophthalmopathy' dsAttr260: type: string format: string description: 'degree of goiter' dsAttr261: type: number format: double description: 'for Graves disease' dsAttr262: type: string format: string description: 'I (0–1 point), II (2–3 points), and III (4–6 points)' dsAttr263: type: number format: double description: 'For arthritits' dsAttr264: type: number format: double description: 'for IgG4-related disease' dsAttr265: type: number format: double description: 'for IgG4-Related disease' dsAttr266: type: number format: double description: 'ELF score (enhanced liver fibrosis)' dsAttr267: type: number format: double description: 'Disease Activity Score-28 for Rheumatoid Arthritis with ESR' dsAttr268: type: number format: double description: 'Ankylosing Spondylitis Disease Activity Score' dsAttr269: type: number format: double description: 'BASFI functional index' dsAttr270: type: number format: double description: 'BASMI measurement index' dsAttr271: type: number format: double description: 'For RA - CDAI' dsAttr272: type: number format: double description: 'The Dermatology life Quality Index (DLQI) is a ten-question questionnaire used to measure the impact of skin disease on the qual' dsAttr273: type: number format: double description: 'The Nail Psoriasis Severity Index (NAPSI) is a numeric, reproducible, objective, simple tool for evaluation of nail psoriasis.' dsAttr274: type: number format: double description: 'health assessment questionnaire–disability index' dsAttr275: type: string format: string description: 'Anti-Smith Antibody Positivity' dsAttr276: type: string format: string description: ' SSA (Ro) or SSB (La) antibodies is consistent with connective tissue disease, including Sjogren syndrome, lupus erythematosus' dsAttr277: type: string format: string description: 'For ITP' dsAttr278: type: string format: string description: 'For ITP' dsAttr279: type: string format: string description: 'AECA: anti-endothelial cell antibodies' dsAttr280: type: number format: double description: 'Checklist Individual Strength' dsAttr281: type: number format: double description: 'Checklist Individual Strength' dsAttr282: type: number format: double description: 'Checklist Individual Strength' dsAttr283: type: number format: double description: 'Checklist Individual Strength' dsAttr284: type: number format: double description: 'IgG index' dsAttr285: type: number format: double description: 'aspartate aminotransferase–to-platelet ratio index' dsAttr286: type: number format: double description: 'FIB-4, fibrosis index' dsAttr287: type: string format: string description: 'water channel protein aquaporin-4 (AQP4)' dsAttr288: type: number format: double description: 'Ranson score for patients with Acute Pancreatitis' dsAttr289: type: number format: double description: 'Balthazar score (for acute pancreatitis)' dsAttr290: type: number format: double description: 'MCTSI Modified Computed Tomography Severity Index' dsAttr291: type: number format: double description: 'bedside index of severity in acute pancreatitis' dsAttr292: type: number format: double description: 'Glasgow severity score' dsAttr293: type: number format: double description: 'degree of disability/dependence after a stroke' dsAttr294: type: number format: double description: 'International Autoimmune Hepatitis Group' dsAttr295: type: number format: double description: 'Bullous Pemphigoid Disease Area Index score' dsAttr296: type: number format: double description: 'BP180-NC16A' dsAttr297: type: number format: double description: 'BP230-CF' dsAttr298: type: number format: double description: 'BPDAI skin activity score' dsAttr299: type: number format: double description: 'Blisters/erosions score' dsAttr300: type: number format: double description: 'Erythema/urticaria score' dsAttr301: type: number format: double description: 'for Bullous pemphigoid' dsAttr302: type: number format: double description: 'ESSDAI EULAR Sjögren Disease Activity Index' dsAttr303: type: number format: double description: 'ESSPRI EULAR Sjögren Patient Reported Index' dsAttr304: type: number format: double description: 'MEDS, mortality in emergency department sepsis' dsAttr305: type: string format: string description: 'ASA, American Society of Anesthesiologists physical status' dsAttr306: type: string format: string description: 'MS(±): fulfilled/not fulfilled IDF (International Diabetes Foundation) criteria for metabolic syndrome' dsAttr307: type: number format: double description: 'SDAI Simple Disease Activity Index' dsAttr308: type: number format: double description: 'VAS-PAIN (0-100mm)' dsAttr309: type: number format: double description: 'For PsA' dsAttr310: type: number format: double description: 'BODE Index' dsAttr311: type: number format: double description: 'SPARCC Spondyloarthritis Research Consortium of Canada Enthesitis Index' dsAttr312: type: number format: double description: 'SJC swollen joint count' dsAttr313: type: number format: double description: 'FEV1/FVC' dsAttr314: type: number format: double description: 'eczema area and severity index' dsAttr315: type: number format: double description: 'investigator’s global assessment' dsAttr316: type: number format: double description: 'visual analogue scale' dsAttr317: type: number format: double description: 'Visual analogur score' dsAttr318: type: number format: double description: 'Forced Ventilatory Capacity (L)' dsAttr319: type: number format: double description: 'BBB impairment' dsAttr322: type: string format: string description: 'positive or negative group' dsAttr323: type: number format: double description: 'Mexican version of the Systemic Lupus Erythematosus Disease Activity Index' dsAttr324: type: number format: double description: 'Systemic Lupus International Collaborating Clinics' dsAttr325: type: number format: double description: 'anti-nuclear antibody' dsAttr326: type: number format: double description: 'Anti-Ro/SSA titre for SLE' dsAttr327: type: number format: double description: 'Anti-La/SSB antibodies' dsAttr328: type: number format: double description: 'anti-Smith antibodies' dsAttr329: type: number format: double description: 'maximal mid-expiratory flow' dsAttr330: type: number format: double description: 'Cytoplasmic anti-neutrophil cytoplasmic antibodies' dsAttr331: type: number format: double description: 'Perinuclear anti-neutrophil cytoplasmic antibodies' dsAttr332: type: number format: double description: 'Anticardiolipin antibody' dsAttr333: type: number format: double description: 'British Isles Lupus Assessment Group' dsAttr334: type: number format: double description: 'antinucleosome antibodies' dsAttr335: type: number format: double description: 'anti-U1 small nuclear ribonucleoprotein' dsAttr336: type: number format: double description: 'antinuclear ribonucleoprotein' dsAttr337: type: number format: double description: 'anti-Sjögren’s syndromerelated (SS) antigen A' dsAttr338: type: number format: double description: 'anti-Sjögren’s syndromerelated (SS) antigen B' dsAttr339: type: number format: double description: 'The 5-item Asthma Control Questionnaire' dsAttr340: type: number format: double description: 'a patient-reported measure of asthma-specific health-related quality of life' dsAttr341: type: number format: double description: 'AM asthma symptom score' dsAttr342: type: number format: double description: 'PM asthma symptom score' dsAttr343: type: number format: double description: 'Charlson Index' dsAttr344: type: number format: double description: 'Elixhauser Index' dsAttr345: type: number format: double description: 'FEV1 reversibility' dsAttr346: type: number format: double description: 'Asthma Control Questionnaire' dsAttr347: type: number format: double description: 'For asthma' dsAttr348: type: number format: double description: 'For asthma' dsAttr349: type: number format: double description: 'ACQ, asthma control questionnaire' dsAttr350: type: number format: double description: 'HADS‐D: depressive symptoms of the Hospital Anxiety and Depression Scale;' dsAttr351: type: number format: double description: 'HADS‐A: anxiety symptoms of the Hospital Anxiety and Depression Scale' dsAttr352: type: number format: double description: 'Modified Borg Scale scores' dsAttr353: type: string format: string description: 'for text data' dsAttr354: type: number format: double description: 'FEF: Forced expiratory flow' dsAttr355: type: number format: double description: 'FEF: Forced expiratory flow' dsAttr356: type: number format: double description: 'The National Institutes of Health Stroke Scale' dsAttr357: type: number format: double description: 'Hamilton Depression Rating Scale' dsAttr358: type: number format: double description: 'Hamilton Anxiety Rating Scale' dsAttr360: type: number format: double description: 'modified British Medical Research Council' dsAttr361: type: number format: double description: 'CAT (COPD assessment test) score' dsAttr362: type: number format: double description: 'Acute Physiology and Chronic Health Evaluation' dsAttr363: type: number format: double description: 'simplified acute physiology score' dsAttr364: type: string format: string description: 'Response Evaluation Criteria in Solid Tumors' dsAttr365: type: number format: double description: 'For Chronic hepatitis C' dsAttr366: type: number format: double description: 'STAI: State-Trait Anxiety Inventory' dsAttr367: type: number format: double description: 'STAI: State-Trait Anxiety Inventory' dsAttr368: type: number format: double description: 'Diabetes Quality of Life' dsAttr369: type: number format: double description: 'For rhinitis' dsAttr370: type: number format: double description: 'Dietary Approaches to Stop Hypertension (range: 0–9, with higher scores indicating better DASH concordance);' dsAttr371: type: number format: double description: 'for asthma' dsAttr372: type: number format: double description: 'RAI (Ritchie’s articular index)' dsAttr373: type: number format: double description: 'SF-MPQ (simplified McGill pain questionnaire)' dsAttr374: type: number format: double description: 'six-point composite disease activity index using erythrocyte sedimentation rate (ESR)' dsAttr375: type: number format: double description: 'six-point composite disease activity index using Creactive protein (CRP)' dsAttr376: type: number format: double description: 'TJC, tender joint count' dsAttr377: type: string format: string description: 'Epstein-Barr virus (EBV)' dsAttr378: type: string format: string description: '0-Dead, 100-Normal' dsAttr379: type: number format: double description: 'disease activity index' dsAttr380: type: number format: double description: 'disease severity scale for systemic sclerosis' dsAttr381: type: number format: double description: 'Juvenile Arthritis Disease Activity Score' dsAttr382: type: number format: double description: 'JSpaDA score' dsAttr383: type: number format: double description: 'sJADAS10score' dsAttr384: type: number format: double description: 'State Trait Anxiety Inventory' dsAttr385: type: number format: double description: 'Active joint count' dsAttr386: type: number format: double description: 'Limited joint count' dsAttr387: type: number format: double description: 'Depressive symptoms (MFQ-C)' dsAttr388: type: number format: double description: 'Juvenile Arthritis Disease Activity Score' dsAttr389: type: number format: double description: 'Childhood Health Assessment Questionnaire' dsAttr390: type: number format: double description: 'Physician global assessment VAS (0–10 cm)' dsAttr391: type: number format: double description: 'Patient general VAS' dsAttr392: type: number format: double description: 'CHAQ disability index' dsAttr393: type: number format: double description: 'CHAQ pain visual analogue score' dsAttr394: type: string format: string description: 'myositis specific autoantibody' dsAttr395: type: number format: double description: 'Modified Systemic Manifestation Score' dsAttr396: type: number format: double description: 'physical function' dsAttr397: type: number format: double description: 'physicians assessment of activity' dsAttr398: type: number format: double description: 'health-related quality of life' dsAttr399: type: number format: double description: 'patients well-being' dsAttr400: type: number format: double description: '71-joint count Juvenile Arthritis Disease Activity Score' dsAttr401: type: number format: double description: 'health assessment questionnaire' dsAttr402: type: number format: double description: 'PGA-A, Physician global assessment of activity' dsAttr403: type: number format: double description: 'PGA-D, Physician Global Assessment of Damage' dsAttr404: type: number format: double description: 'mLoSSI, modified Localized Scleroderma Skin Score' dsAttr405: type: number format: double description: 'LoSDI, Localized Scleroderma Damage Index' dsAttr406: type: string format: string description: 'anti-ssDNA, anti-single stranded DNA antibodies' dsAttr407: type: string format: string description: 'AHA, anti-histone antibodies' dsAttr408: type: number format: double description: 'Patient-GA, patient Global Assessment of disease impact' dsAttr409: type: number format: double description: 'Parent-GA, parent Global Assessment of disease impact' dsAttr410: type: number format: double description: 'CMAS, Childhood Myositis Assessment Scale' dsAttr411: type: number format: double description: 'DAS total' dsAttr412: type: number format: double description: 'DAS muscle' dsAttr413: type: number format: double description: 'DAS skin' dsAttr414: type: string format: string description: 'MSA antibodies (Myositis-specific antibodies)' dsAttr415: type: number format: double description: 'Manual muscle testing of 8 muscle groups' dsAttr416: type: number format: double description: 'SMA motor score (HMFSE, 0-66) (Hammersmith Functional Motor Scale-Expanded)' dsAttr417: type: string format: string description: 'on tumor cells' dsAttr418: type: string format: string description: 'seropositivity for SARS-CoV-2 IgG antibodies' dsAttr419: type: number format: double description: 'viral load' dsAttr420: type: string format: string description: 'Anti-centromere antibodies in serum' dsAttr421: type: string format: string description: 'Anti-Scl-70 antibodies in serum' dsAttr422: type: number format: double description: 'viral load i CSF' dsAttr423: type: string format: string description: 'Anti-Ro52 antibodies seropositivity' dsAttr424: type: string format: string description: 'anti-Ribonucleoprotein' dsAttr425: type: string format: string description: 'Anti-Phospholipids i.e. for Lupus nephritis' dsAttr426: type: string format: string description: 'WHO Class i.e. for Lupus nephritis' dsAttr427: type: string format: string description: 'Non-renal SLEDAI i.e. for Lupus nephritis' dsAttr428: type: string format: string description: 'anti Acetylcholine receptor in sera' dsAttr429: type: number format: double description: 'AchR Acetylcholine receptor in sera titer' dsAttr430: type: string format: string description: 'Myasthenia Gravis Foundation of America' dsAttr431: type: string format: string description: 'for Myastenia gravis' dsAttr432: type: string format: string description: 'high-avidity antinuclear antibody (ANA) of the IgG isotype' dsAttr433: type: number format: double description: 'Autoimmune Bullous Skin Disorder Intensity Score' dsAttr434: type: number format: double description: 'Anti-Desmoglein1 antibody' dsAttr435: type: number format: double description: 'anti-Desmoglein3 AB' dsAttr436: type: number format: double description: 'FSS: Fatigue Severity Scale' dsAttr437: type: number format: double description: 'SpO2: oxygen saturation' dsAttr438: type: string format: string description: 'HLA-B51 positivity' dsAttr439: type: number format: double description: 'Myasthenia Gravis Activities of Daily Living' dsAttr440: type: string format: string description: 'For MDS' dsAttr441: type: string format: string description: 'WPSS: WHO classification-based Prognostic Scoring System' dsAttr442: type: number format: double description: 'the total amount of iron in your blood plus the UIBC (Unsaturated iron-binding capacity)' dsAttr443: type: number format: double description: 'TSAT = transferrin saturation' dsAttr444: type: string format: string description: 'IPSS-R (Revised International Prognostic Scoring System)' dsAttr445: type: string format: string description: 'IPSS (International Prognostic Scoring System)' dsAttr446: type: number format: double description: 'Unsaturated Iron Binding Capacity' dsAttr447: type: number format: double description: 'Homeostasis model assessment of insulin resistance' dsAttr448: type: number format: double description: 'Homeostasis model assessment of insulin resistance' dsAttr449: type: number format: double description: 'Homeostasis model assessment of insulin resistance' dsAttr450: type: number format: double description: 'key features of acromegaly: signs and symptoms (S), associated comorbidities (A), GH levels (G), IGF-1 levels (I), and the Tumor' dsAttr451: type: number format: double description: 'Lung RV in liters' dsAttr452: type: number format: double description: 'Lung residual volume (%)' dsAttr453: type: number format: double description: ' The five-point Fleischner grading system offers the possibility to more precisely grade the visual severity of parenchymal emph' dsAttr454: type: number format: double description: 'Total lung capacity' dsAttr455: type: number format: double description: 'maximum expiratory flow at 25% of vital capacity' dsAttr456: type: number format: double description: 'maximum expiratory flow at 50% of vital capacity' dsAttr457: type: number format: double description: 'maximum expiratory flow at 75% of vital capacity' dsAttr458: type: string format: string description: 'Alpha-1 antitrypsin genotype, i.e. ZZ, ZM etc.' dsAttr459: type: number format: double description: 'FEV1/FVC (% predicted)' dsAttr460: type: string format: string description: 'French- American-British classification' dsAttr461: type: number format: double description: 'by FibroScan' dsAttr462: type: number format: double description: 'biochemical severity scoring system based on liver function tests in predicting the extent of liver fibrosis/cirrhosis' dsAttr463: type: string format: string description: 'Smooth muscle antibodies (SMA)' dsAttr464: type: string format: string description: 'IPSS-RA age-adjusted calculation of revised IPSS' xml: name: query_data securitySchemes: cytocon_auth: type: oauth2 flows: implicit: authorizationUrl: https://cytocon.insysbio.com/oauth/token scopes: read:diseases: read diseases read:tissues_types: read tissue types read:species: read species read:markers: read markers read:patient_group_attributes: read patient group attributes read:disease_attributes: read disease attributes read:query_data: read query data read:query_data_headers: read query headers data api_key: type: apiKey name: Authorization in: header